1 in 5

older Australians may have marginal B6 status affecting mood and nerve function

NHMRC Nutrient Reference Values, 2014

Good reasons to test

Unexplained fatigue, mood changes, or irritability
Peripheral neuropathy or tingling in hands and feet
Elevated homocysteine

Vitamin B6 (Pyridoxine)

No fasting required. Any time of day — avoid B6 supplements for 24 hours before testing if monitoring baseline levels Results arrive in 3-5 business days, explained in plain language in your dashboard. Most results sit within the usual range - that is still useful, and anything unexpected supports a conversation with your healthcare practitioner.

Targeted Testing

B6

Pyridoxine — key to mood, immunity, and homocysteine metabolism

$89one-off, no subscription

NATA-accredited pathology
No GP referral needed
Results in 3-5 business days
Collect at 1,900+ centres

Why this test

Vitamin B6 is essential for making serotonin and noradrenaline — deficiency may contribute to depression, fatigue, and nerve symptoms.

Vitamin B6 (pyridoxine) is involved in over 100 enzyme reactions, including the synthesis of neurotransmitters (serotonin, dopamine, GABA), haemoglobin production, and homocysteine metabolism. Deficiency is more common in older adults, people with kidney disease, those taking certain medications (oral contraceptives, isoniazid), and people with high alcohol intake. Notably, very high supplemental doses of B6 can cause toxicity and peripheral neuropathy.

Understanding your results

Within reference range

Your B6 level is within the expected range

High-normal

On the higher side — if you take B6 supplements, consider reviewing your dose with your healthcare practitioner

Below reference range

Low B6 may contribute to mood changes, fatigue, or nerve symptoms — discuss with your healthcare practitioner

Above reference range

High B6 from supplementation can cause peripheral neuropathy — discuss with your healthcare practitioner

Reference ranges vary by laboratory and personal context. Your result is shown against the lab's range in your dashboard, alongside what it means.

How it works

TODAY

Order online

Pick a test or panel and check out. No GP referral, no waiting room.

THIS WEEK

One quick visit

Walk into one of 1,900+ NATA-accredited collection centres. A single blood draw is all it takes.

IN 2–5 DAYS

Clear results

We translate your results into plain language in your dashboard - what each marker means, and what is in range.

ONGOING

Track over time

Retest when it matters and watch your trends, so you can see what is actually changing.

Yes. You can order a B6 test online from Clarity Labs without a GP referral. It's $89, collected at any of 1,900+ NATA-accredited centres across Australia, with results in 3-5 business days via your secure online dashboard.

A B6 test is $89 at Clarity Labs — a one-off price with no subscription or membership. That covers your pathology request form and collection at any of 1,900+ NATA-accredited centres nationwide.

Yes — unlike most water-soluble vitamins, high-dose B6 supplementation (typically >100–200mg per day) over prolonged periods can cause sensory neuropathy. This is why monitoring levels is important for people taking B6 supplements.

Yes. Oestrogen-containing contraceptives can reduce B6 status in some women. If you have been on the pill for several years and experience mood or energy changes, B6 is worth checking.

Every 6-12 months if you take high-dose B6 supplements (to monitor for toxicity risk). Otherwise, a baseline with a repeat only if new symptoms develop or your medication or diet changes significantly.

NATA-accredited pathologyCollected through Sonic Healthcare1,900+ collection centresNo GP referral needed

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This information is for general education and is not medical advice, diagnosis, or treatment. Results are best interpreted with a qualified healthcare practitioner in the context of your symptoms and history.